Abarelix

Brand name(s):
Plenaxis

What is the most important information I should know about abarelix?
In some cases, the use of abarelix has resulted in serious allergic reactions.
An allergic reaction may occur after any injection of the medication,
including, but not limited to the first dose. Patients should be observed
in the doctor’s office for at least 30 minutes following each dose so
that immediate treatment of an allergic reaction can be obtained if needed.

Treatment with abarelix may become less effective over time in some patients.
Monitoring blood levels of testosterone will be done on a regular basis
with blood tests to monitor the effectiveness of the medication.
abarelix is not intended for use by women. abarelix is in the FDA pregnancy
category X. This means that abarelix will cause birth defects in an unborn
baby. Do not use this medication if you are pregnant or if you could become
pregnant during treatment.
What is abarelix?

abarelix reduces the amount of testosterone produced in the body.

abarelix is used in the palliative treatment of advanced prostate cancer.

abarelix may also be used for purposes other than those listed in this
medication guide.
What should I discuss with my healthcare provider before using abarelix?

Before using abarelix, tell your doctor if you

* have irregular heartbeats;
* have liver problems;
* have osteoporosis; or
* weigh more than 225 pounds.

You may not be able to use abarelix, or you may require a dosage adjustment
or special monitoring during treatment.
abarelix is not intended for use by women. abarelix is in the FDA pregnancy
category X. This means that abarelix will cause birth defects in an unborn
baby. Do not use this medication if you are pregnant or if you could become
pregnant during treatment. abarelix is not intended for use by women.
It is not known whether abarelix passes into breast milk. Do not use this
medication without first talking to your doctor if you are breast-feeding
a baby.
How should I use abarelix?

abarelix must be administered by a qualified healthcare provider.

abarelix is administered as an injection into the muscle.
In some cases, the use of abarelix has resulted in serious allergic reactions.
An allergic reaction may occur after any injection of the medication,
including, but not limited to the first dose. Patients should be observed
in the doctor’s office for at least 30 minutes following each dose so
that immediate treatment of an allergic reaction can be obtained if needed.

Treatment with abarelix may become less effective over time in some patients.
Monitoring blood levels of testosterone will be done on a regular basis
with blood tests to monitor the effectiveness of the medication.

It is important to use abarelix regularly to get the most benefit.

abarelix vials for injection should be stored at room temperature away
from moisture and heat.
What happens if I miss a dose?

Contact your doctor if you miss a dose of abarelix.
What should I avoid while using abarelix?

There are no restrictions on food, beverages, or activities while using
abarelix. Follow any special instructions given by your doctor.
What are the possible side effects of abarelix?
In some cases, the use of abarelix has resulted in serious allergic reactions.
An allergic reaction may occur after any injection of the medication,
including, but not limited to the first dose. Patients should be observed
in the doctor’s office for at least 30 minutes following each dose so
that immediate treatment of an allergic reaction can be obtained if needed.

Other, less serious side effects may be more likely to occur. Talk to
your doctor if you experience

* hot flashes;
* sleep disturbances;
* breast enlargement or pain;
* diarrhea or constipation;
* swelling;
* nausea;
* dizziness;
* headache;
* fatigue; or
* changes with or difficulty urinating.

Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially
bothersome.
What other drugs will affect abarelix?

It is not known whether abarelix will interact with other medicines.
Talk to your doctor and pharmacist before taking any prescription or over-the-counter
medicines, including herbal products during treatment with abarelix.
Where can I get more information?

Your pharmacist has additional information about abarelix written for
health professionals that you may read.
What does my medication look like?

Abarelix is available with a prescription under the
brand name plenaxis as an injection. Other brand or generic
formulations may also be available. Ask your pharmacist any questions
you have about this medication, especially if it is new to you.